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Ximino Warnings and Precautions

Before taking Ximino, make sure your healthcare provider is aware of your medical history, including any problems with your vision, liver, or kidneys. Other warnings associated with Ximino include safety precautions for women who are pregnant or breastfeeding. Also, you may not be able to take this acne medicine if you have certain allergies or if you are taking certain medications.

What Should I Tell My Healthcare Provider?

You should talk with your healthcare provider prior to taking Ximino™ (minocycline hydrochloride) if you have:
  • Kidney disease, such as kidney failure (renal failure)
  • Liver disease, such as hepatitis, cirrhosis, or liver failure
  • Vision problems, such as blurred vision
  • Any allergies, including to medications, foods, dyes, or preservatives.
Also, let your healthcare provider know if you are:
  • Pregnant or thinking of becoming pregnant
  • Breastfeeding.
You should also tell your healthcare provider about all other medications you are taking, including prescription and nonprescription medicines, vitamins, and herbal supplements.

Specific Precautions and Warnings With Ximino

Some warnings and precautions to be aware of prior to taking Ximino include:
  • All antibiotics, including Ximino, can disrupt the normal bacteria in the digestive tract, allowing undesirable bacteria to overgrow. This could lead to a potentially life-threatening problem known as pseudomembranous colitis. Contact your healthcare provider if you experience bloody or watery diarrhea, which can be signs of this serious problem. Pseudomembranous colitis can occur for several months after you stop taking Ximino.
  • Tetracycline antibiotics, including Ximino, may cause permanent discoloration of teeth if used when the teeth are still developing (usually up to age eight). Ximino is only approved for use in children age 12 and older. It should not be used in children under the age of eight.
  • Ximino may cause intracranial hypertension, which is increased pressure inside the skull. This condition may lead to permanent or severe vision loss. Contact your healthcare provider if you experience symptoms of intracranial hypertension, such as headaches, blurred vision, and dizziness. Usually these symptoms will go away after Ximino is stopped.
  • Tell your healthcare provider if you experience a fever, rash, feelings of weakness or discomfort, or joint pain while taking Ximino. These could be signs that you are developing an autoimmune disease, which may occur with long-term Ximino use.
  • Ximino may increase your sensitivity to the sun, which could put you at risk for severe sunburn. Try to avoid unnecessary sunlight exposure, including natural sunlight and tanning beds, while taking this medication. If you go out into the sun, wear loose-fitting clothing on as much of your skin as possible and use a sunscreen with a rating of SPF 45 or higher.
  • There have been reports of serious skin rashes and other allergic reactions with the use of minocycline, the active ingredient of Ximino. Seek immediate medical attention if you develop any signs of an allergic reaction, such as:
    • A rash or hives
    • Itching
    • Swelling of the lips or throat
    • Wheezing
    • Difficulty breathing.
  • Ximino may cause darkening of many body organs, including the nails, skin, eyes, and teeth. Contact your healthcare provider if you experience these reactions. While many of the darkened areas will return to normal after Ximino is stopped, tooth discoloration may be permanent.
  • Ximino may cause dizziness, lightheadedness, or a spinning sensation (vertigo). Avoid driving or operating heavy machinery if you experience these symptoms.
  • There have been reports of liver problems, including hepatitis and liver failure, in people using minocycline (the active ingredient of Ximino). Contact your healthcare provider immediately if you develop any signs of liver problems, such as:
    • Dark urine
    • Loss of appetite
    • Fatigue or excessive tiredness
    • Upper-right abdominal (stomach) pain
    • Yellowing of the whites of the eyes or skin (jaundice).
  • If you have kidney disease, your body may handle Ximino differently than usual. Your healthcare provider may choose to give you a lower Ximino dose.
  • Taking antibiotics, such as Ximino, may cause other infections to occur, including yeast or fungal infections. If you notice symptoms of a fungal or yeast infection, contact your healthcare provider.
  • Ximino is a pregnancy Category D medication, which means it may harm an unborn baby (see Ximino and Pregnancy for more information).
  • Ximino passes through breast milk. Therefore, if you are breastfeeding or plan to start, discuss this with your healthcare provider before taking this drug (see Ximino and Breastfeeding).

Ximino Acne Medication

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