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Solodyn Warnings and Precautions

When using Solodyn, precautions should be taken to avoid excessive sun exposure, as this drug may increase your sensitivity to sunlight, making you more prone to sunburn. Other warnings with Solodyn include the possibility of drug interactions and an increased risk of side effects for people with liver or kidney disease, as well as vision problems.

What Should I Tell My Healthcare Provider?

You should talk with your healthcare provider prior to using Solodyn® (minocycline hydrochloride) if you have:
  • Kidney disease, such as kidney failure (renal failure)
  • Liver disease, such as hepatitis, cirrhosis, or liver failure
  • Vision problems, such as blurred vision
  • Any allergies, including to medications, foods, dyes, or preservatives.
Also, let your healthcare provider know if you are:
  • Pregnant or thinking of becoming pregnant
  • Breastfeeding.
You should also tell your healthcare provider about any other medications you are taking, including prescription and nonprescription medicines, vitamins, and herbal supplements.

Specific Precautions and Warnings With Solodyn

Some warnings and precautions to be aware of with this drug include the following:
  • Tetracycline antibiotics, including Solodyn, may cause permanent discoloration of the teeth if used when the teeth are still developing, which is usually up to age eight. This medication is only approved for use in people over the age of 12. It should not be used in children under the age of eight.
  • Solodyn may cause intracranial hypertension, which is increased pressure inside the skull. This condition may lead to permanent or severe vision loss. Contact your healthcare provider if you experience symptoms of intracranial hypertension, such as headache, blurred vision, and dizziness. Usually these symptoms will go away once the medication is stopped.
  • Tell your healthcare provider if you experience fever, rash, feelings of weakness or discomfort, or joint pain while taking Solodyn. These could be signs that you are developing an autoimmune disease, which may occur with long-term Solodyn use.
  • This medication may increase your sensitivity to the sun, which could put you at risk for a serious sunburn. Try to avoid unnecessary sunlight exposure (both outdoor and with tanning beds) while taking this medication. If you go out in the sun, wear loose-fitting clothing on as much of your skin as possible and use a sunscreen with a rating of SPF 45 or higher.
  • There have been reports of serious skin rashes and other allergic reactions with the use of minocycline (the active ingredient in Solodyn). Seek immediate medical attention if you develop any signs of an allergic reaction, such as:
    • Rash
    • Hives
    • Itching
    • Swelling of the lips or throat
    • Wheezing
    • Difficulty breathing.
  • Solodyn may cause darkening of many body organs, including the nails, skin, eyes, and teeth. Contact your healthcare provider if you experience these reactions. While many of the darkened areas will return to normal after the medication is stopped, tooth discoloration may be permanent.
  • Solodyn may cause dizziness, lightheadedness, or a spinning sensation (vertigo). Avoid driving or operating heavy machinery if you experience these symptoms.
  • There have been reports of liver problems, including hepatitis and liver failure, in people using minocycline (the active ingredient in Solodyn). Contact your healthcare provider immediately if you develop any signs of liver problems, including:
    • Dark urine
    • Loss of appetite
    • Fatigue or excessive tiredness
    • Pain in the right upper part of the stomach
    • Yellowing of the whites of the eyes or skin (jaundice).
  • All antibiotics (including Solodyn) can disrupt the normal bacteria in the digestive tract, allowing undesirable bacteria to overgrow. This could lead to a potentially life-threatening problem known as pseudomembranous colitis. Contact your healthcare provider if you experience bloody or watery diarrhea, which can be signs of this serious problem. Pseudomembranous colitis can occur for several months after you stop taking Solodyn.
  • If you have kidney disease, your body may handle this drug differently than usual. Your healthcare provider may choose to give you a lower Solodyn dosage.
  • Taking antibiotics may cause other infections to occur, including yeast or fungal infections. If you notice symptoms of a fungal or yeast infection, contact your healthcare provider.
  • Solodyn may react with several other medications (see Solodyn Drug Interactions).
  • Solodyn is a pregnancy Category D medication, which means it may harm an unborn baby (see Solodyn and Pregnancy for more information).
  • This product passes through breast milk. Therefore, if you are breastfeeding or plan to start, discuss this with your healthcare provider before using Solodyn (see Solodyn and Breastfeeding).

Solodyn Drug Information

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