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Solodyn and Pregnancy

When women took the active ingredient in Solodyn (minocycline) during pregnancy, reported problems included missing or smaller-than-normal arms and legs. As a result, the FDA recommends that women not take this drug when pregnant. The benefits Solodyn presents as an acne treatment do not outweigh the risks -- another, safer treatment option should be pursued instead.

Can Pregnant Women Use Solodyn?

Solodyn® (minocycline hydrochloride) is a prescription medication used to treat the red, pus-filled pimples from moderate-to-severe acne. It may cause harm to an unborn baby. Solodyn should not be used during pregnancy because the risks outweigh the benefits.

What Is Pregnancy Category D?

The U.S. Food and Drug Administration (FDA) uses a category system to classify the possible risks to a fetus when a specific medicine is taken during pregnancy. Pregnancy Category D is a classification given to medicines that have been shown to present a risk to the fetus in studies of pregnant women but may still offer benefits that outweigh the risks the drug presents.
In other words, a pregnancy Category D medicine may still be given to a pregnant woman if the healthcare provider believes that the benefits to the woman outweigh the possible risks to the unborn child.
There have been reports of birth defects, such as missing or reduced size of arms and legs, in the babies of women who took minocycline (the active ingredient of Solodyn) during pregnancy. It is unclear, however, if these defects were due to minocycline or something else.
If taken during the period of tooth development, which occurs from the second half of pregnancy through the age of eight, Solodyn may cause permanent tooth discoloration. The discoloration leads to teeth that have a yellow-gray-brown color. Cases of insufficient amounts of tooth enamel have also been reported.
Pregnancy and Pain

Solodyn Drug Information

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