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Minocin Warnings and Precautions

There are several precautions and warnings to be aware of before starting treatment with Minocin. For example, you should talk to your healthcare provider if you have any medical conditions, such as liver disease, kidney disease, or frequent yeast infections, before using this prescription antibiotic. Warnings also apply to people with certain allergies and women who are pregnant or breastfeeding.

What Should I Tell My Healthcare Provider Before Using Minocin?

You should talk to your healthcare provider prior to taking Minocin® (minocycline hydrochloride) if you have:
  • Liver disease, such as liver failure, cirrhosis, or hepatitis
  • Kidney disease, such as kidney failure (renal failure)
  • Frequent yeast infections
  • Any other allergies, including allergies to foods, dyes, or preservatives.
Also, let your healthcare provider know if you are:
  • Pregnant or thinking of becoming pregnant
  • Breastfeeding.
Make sure to tell your healthcare provider about any other medicines you are taking, including prescription and non-prescription medicines, vitamins, and herbal supplements.

Specific Minocin Precautions and Warnings

Some precautions and warnings to be aware of prior to taking this medicine include the following:
  • Many antibiotics have been known to cause pseudomembranous colitis (a very severe diarrhea due to overgrowth of a certain bacteria). This is a serious condition that may potentially be fatal. If you experience severe, bloody, or prolonged diarrhea, contact your healthcare provider immediately.
  • Minocin is considered a pregnancy Category D medicine. This means that there is significant risk to an unborn baby. If you are pregnant, discuss these risks with your healthcare provider before using Minocin (see Minocycline and Pregnancy for more information). In some rare situations, it may be appropriate for a pregnant woman to take this medication.
  • To avoid damage to the esophagus while taking Minocin, make sure to take the medication with plenty of fluids. Do not take this medication lying down, and do not lie down immediately after taking this medication. These measures are necessary to make sure that the Minocin capsule does not accidentally stick in your throat, where it could cause significant irritation and damage.
  • Taking Minocin during pregnancy or before the age of 8 years old may cause permanent discoloration of teeth in the infant or child.
  • Minocin can interact with certain medications (see Minocin Drug Interactions).
  • If you have kidney disease or severe liver disease, your healthcare provider may choose to give you a lower-than-normal dose of Minocin or not prescribe the drug at all.
  • If you are breastfeeding, it is important to know that Minocin passes through breast milk. Therefore, if you are breastfeeding or plan to start breastfeeding, make sure to check with your healthcare provider before taking Minocin (see Minocycline and Breastfeeding).
  • While taking antibiotics such as Minocin, other infections have been known to occur (vaginal yeast infections, etc.). If you notice symptoms unrelated to your original condition, talk to your healthcare provider.
  • Antibiotics have been known to cause increased pressure in the skull. This usually stops when the antibiotic is discontinued. Make sure to talk to your healthcare provider if you experience any of the following while taking Minocin:


    • Headaches
    • Blurred vision
    • Nausea
    • Vomiting
    • Dizziness.


  • Skin reactions that resemble serious sunburns may occur if you are exposed to sunlight while taking Minocin. Try to avoid unnecessary sunlight exposure while taking this antibiotic. If sunlight exposure is unavoidable, cover as much of your skin as possible (long sleeves, long pants, or a hat), and use a sunscreen with a rating of SPF 45 or higher.

Minocin Antibiotic Information

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