Cases of moderate-to-severe acne can often be treated with the prescription drug Solodyn. As an antibiotic, it is believed to work by interfering with bacteria's ability to grow and multiply. The medicine comes in tablet form and is taken once a day. Most people have no problems with it; however, side effects are possible. Common ones include headache, dizziness, and itching.
What Is Solodyn?
Solodyn® (minocycline hydrochloride) is a prescription antibiotic licensed to treat the red, inflamed, pus-filled bumps of moderate-to-severe acne in people 12 years of age and older. It belongs to a class of antibiotics called tetracyclines.
Solodyn is made by WellSpring Pharmaceutical Canada Corp. for Medicis Pharmaceutical Corporation.
How Does Solodyn Work?
Like other tetracycline antibiotics, Solodyn interferes with bacteria's ability to make proteins, which impedes bacterial growth and multiplication. It is unknown, however, if this action is responsible for its effects on acne.
The exact mechanism by which Solodyn treats acne is unknown. The medication is believed to affect the bacteria that cause acne and reduce the associated inflammation, resulting in fewer, less-inflamed pimples and red bumps.
In clinical studies, Solodyn was shown to reduce the number of acne pimples, as well as the overall appearance of acne, more than a placebo (a "sugar pill" with no active ingredient). In these studies, people who took the medication for 12 weeks had a greater reduction in inflammatory acne sores, on average, than those who took the placebo.
In addition, up to 17.3 percent of the people using Solodyn had their acne rated as "clear" or "almost clear" after 12 weeks, compared to up to 9.5 percent of those using the placebo.
National Library of Medicine (US). Hazardous Substances Data Bank (HSDB). NLM Web site. Available at: http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?HSDB. Accessed February 23, 2011.
National Library of Medicine (US). Drugs and Lactation Database (LactMED). NLM Web site. Available at: http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?LACT. Accessed February 23, 2011.
Food and Drug Administration, Center for Drug Evaluation and Research. Electronic orange book: approved drug products with therapeutic equivalence evaluations. FDA Web site. Available at: http://www.fda.gov/cder/ob/. Accessed August 14, 2012.
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