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Signs that you are experiencing a potentially serious side effect of Solodyn include unexplained wheezing, trouble breathing, and severe stomach pain. These problems likely require medical attention. Fortunately, most reactions to this drug are mild and easily treated -- if they even occur at all. For example, in clinical studies, only 9 percent experienced dizziness and mild tiredness.

An Introduction to Solodyn Side Effects

As with any medicine, Solodyn® (minocycline hydrochloride) can cause side effects. However, not everyone who uses the medication will have problems. In fact, most people tolerate it quite well. If side effects do occur, in most cases, they are minor and either require no treatment or are treated easily by you or your healthcare provider.
(This article covers many, but not all, of the possible side effects with Solodyn. Your healthcare provider can discuss a more complete list with you.)

Common Side Effects of Solodyn

Solodyn has been studied extensively in clinical trials. In these studies, the side effects that occurred in a group of people taking Solodyn were documented and then compared to those that occurred in a similar group of people taking a placebo (a "sugar pill" with no active ingredients).
In these studies, the most commonly reported Solodyn side effects included:
  • Headache -- in up to 23 percent of people
  • Tiredness -- up to 9 percent
  • Dizziness -- up to 9 percent
  • Itching -- up to 5 percent
  • General feelings of discomfort (malaise) -- up to 4 percent
  • Changes in mood -- up to 3 percent
  • Drowsiness -- up to 2 percent
  • Ringing in the ears -- up to 2 percent.
Other common reactions (occurring in 1 percent of people) included:
  • Joint pain
  • Muscle pain
  • A spinning sensation
  • Dry mouth.
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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