Acne Home > Differin Uses

If you have acne, your healthcare provider may prescribe Differin. This medication is approved for use in adults and children as young as 12 years old. When using this medication for acne, your skin may look worse temporarily; it usually takes about a month for skin appearance to improve. There are also a few "off-label" uses for Differin, including the treatment of rosacea and fine wrinkles.

What Is Differin Used For?

Differin® (adapalene) is a prescription medication licensed to treat acne. It is also occasionally used "off-label" for a few different, unapproved uses.
Differin is one of many different prescription acne medications currently available. Like many acne medications, Differin can make the skin appear worse before it gets better. Often, the skin may become irritated, red, and flaky. However, this usually gets better with time, and clearer skin should be noticeable within a month or so.
If your skin has not improved within two to three months, you should be reevaluated by your healthcare provider -- it's possible that a different treatment strategy will be necessary.
Your healthcare provider might recommend that you use Differin alone or with another acne medication. Because Differin is applied in the evening (typically at bedtime), your healthcare provider may recommend a different type of acne treatment for use in the morning.

How Does Differin Work?

Differin belongs to a group of medications known as retinoids, meaning it is chemically related to vitamin A. Some other well-known retinoids include Retin-A® and Accutane®.
Differin and other retinoids are thought to work by suppressing inflammation and slowing down the rapid growth of skin cells.
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
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