Acne Home > Clindamycin Side Effects

Nausea, vomiting, and diarrhea are some of the most common problems reported with the oral or injectable forms of clindamycin. Side effects of the skin products may include dryness, redness, or itching. While most problems do not require medical attention, you should contact your healthcare provider if you experience severe or bloody diarrhea, decreased urine production, or difficulty breathing.

An Introduction to Clindamycin Side Effects

Just like any medicine, clindamycin can cause side effects. However, not everyone who takes the medication will have problems. In fact, some people tolerate it quite well. If side effects do occur, in many cases, they are minor and either require no treatment or are easily treated by you or your healthcare provider.
(This article covers many, but not all, of the possible side effects with clindamycin. Your healthcare provider can discuss a more complete list of side effects with you.)

Possible Side Effects of Clindamycin

For many medications, the prescribing information carefully explains the exact percentage of side effects that were seen in clinical trials. However, the prescribing information for almost all older medications, including many clindamycin medications, contains only vague information on potential side effects, with no percentages provided. Therefore, it can be difficult to know exactly how common or how rare problems with such medications may be. In addition, the many different forms of clindamycin may have significantly different side effects.
Some of the possible side effects of oral or injectable clindamycin are thought to include:
The most common problems seen with topical clindamycin products (applied to the skin for acne treatment) include:
  • Dryness
  • Redness
  • Burning
  • Itching
  • Peeling.
The most common side effect of clindamycin vaginal products is vaginal fungal infection, such as a yeast infection.
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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