Acne Home > Accutane Interactions

When certain medicines are taken with Accutane, interactions could occur and cause potentially serious complications. For example, some drug interactions may result in a certain type of high blood pressure in the head or increase your risk of osteoporosis. Some of the medications that can negatively interact with Accutane include certain antibiotics, corticosteroids, and progestin-only birth control pills.

An Overview of Accutane Interactions

Accutane® (isotretinoin) can potentially interact with several other medications. Some of the medicines that may lead to Accutane drug interactions include:
  • Certain antibiotics, such as:
  • Corticosteroids, such as:
    • Betamethasone (Celestone®)
    • Cortisone
    • Dexamethasone (Decadron®)
    • Fludrocortisone (Florinef®)
    • Hydrocortisone (Cortef®)
    • Methylprednisolone (Depo-Medrol®, Medrol®)
    • Prednisolone (Orapred®, Pediapred®)
    • Prednisone
    • Triamcinolone (Kenalog®, Aristospan®)
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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