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Epiduo Warnings and Precautions

Although it is considered an effective acne medication for many people, Epiduo can cause problems. For example, this product can make your skin more sensitive to the sun. Also, you may not be able to safely use Epiduo if you have eczema or certain allergies. Before starting treatment with Epiduo, talk to your doctor about the specific warnings and precautions that apply to you.

What Should I Tell My Healthcare Provider?

You should talk with your healthcare provider prior to using Epiduo® (adapalene/benzoyl peroxide) if you have:
  • Eczema
  • A sunburn
  • Sensitivity to the sun or go out in the sun often
  • Any allergies, including to foods, dyes, or preservatives.
Also, let your healthcare provider know if you are:
  • Pregnant or thinking of becoming pregnant
  • Breastfeeding.
Make sure to tell your healthcare provider about any other medications you are taking, including other prescription and nonprescription medicines, vitamins, and herbal supplements.

Specific Precautions and Warnings for Epiduo

Some of the warnings and precautions to be aware of with this product include the following:
  • Epiduo should not be applied to cuts, scrapes, sores, eczema, or sunburned skin.
  • Your skin will be more sensitive to the sun while you are using Epiduo. For this reason, you should avoid exposure to the sun and to artificial sun, including sunlamps and tanning beds, when you use this medication. If you do go out in the sun, use a sunscreen and protective clothing, such as a hat. Your healthcare provider can recommend an appropriate sunscreen for your skin type.
  • Your skin may be more sensitive to the wind or cold while you are using Epiduo. Talk to your healthcare provider if your skin becomes extremely irritated from the wind or cold.
  • If you get a sunburn in an area of the skin where you normally apply Epiduo, stop using the medication until your sunburn heals.
  • Epiduo can cause your skin to become dry. If your skin becomes too dry, try using a moisturizer.
  • Any area of the skin treated with Epiduo should not be waxed, as this may cause skin damage and irritation.
  • Do not use Epiduo more often than prescribed, as this may increase your risk for skin irritation.
  • Epiduo is unlikely to interact with other medications. However, using Epiduo with some skin care products can increase your risk for skin irritation or dryness (see Epiduo Drug Interactions).
  • Epiduo is considered a pregnancy Category C medication. This means that it may not be safe to use during pregnancy. Talk with your healthcare provider about the risks and benefits of using Epiduo during pregnancy (see Epiduo and Pregnancy).
  • It is not known if Epiduo passes through breast milk. Therefore, if you are breastfeeding or plan to start breastfeeding, talk to your healthcare provider about using Epiduo (see Epiduo and Breastfeeding).

Epiduo Medication Information

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