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Dynacin and Pregnancy

Due to the risk of problems such as tooth discoloration and, in rare cases, birth defects, pregnant women are advised to avoid Dynacin (minocycline hydrochloride). In some cases, such as if no safer antibiotic is available, a healthcare provider may prescribe Dynacin to a pregnant woman. However, it should only be used during pregnancy when the benefits outweigh the risks.

Can Pregnant Women Use Dynacin?

Dynacin® (minocycline hydrochloride) is a prescription medication used to treat many different bacterial infections, including severe acne. It belongs to the tetracycline class of antibiotics. If used during pregnancy, Dynacin could harm an unborn child.

What Is Pregnancy Category D?

The U.S. Food and Drug Administration (FDA) uses a category system to classify the possible risks to a fetus when a specific medicine is taken during pregnancy. Pregnancy Category D is given to medicines that have been shown to present a risk to the fetus in studies of pregnant women but may still offer benefits that outweigh the risks the drug presents. A pregnancy Category D medicine may still be given to a pregnant woman if the healthcare provider believes that the benefits to the woman outweigh the possible risks to the unborn child.
Dynacin may cause permanent tooth staining (a yellow/gray/brown color) if taken during the period of tooth development. Insufficient tooth enamel has also been reported. Tooth development occurs from the second half of pregnancy up to age eight. For this reason, Dynacin is not recommended for use in children younger than eight, or during pregnancy, when the medication can pass to the developing fetus.
There have also been rare reports of birth defects, including limb reduction, associated with the use of minocycline (the active ingredient of Dynacin) during pregnancy. An infant with limb reduction has underdeveloped arms or legs, which can lead to a smaller-than-normal or completely missing arm or leg. It is not clear, however, if these defects are actually caused by minocycline use or by something else.
In general, Dynacin is not recommended for use during pregnancy. There may be times, however, when the benefits of the medication outweigh the potential risks. This could occur if no safer antibiotics are available to treat a serious infection. The risks of Dynacin use during pregnancy clearly outweigh the benefits of treating acne, however.
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Dynacin Antibiotic Information

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