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Duac Warnings and Precautions

If you are using Duac, it is important to know that this skin gel can cause problems, such as an increased sensitivity to the sun, skin reactions, and skin or nail infections. Other safety precautions with Duac involve warnings about using this drug while pregnant or breastfeeding. Also, you should not use this acne treatment if you have Crohn's disease or ulcerative colitis.

What Should I Tell My Healthcare Provider?

You should talk with your healthcare provider prior to using Duac® (clindamycin/benzoyl peroxide) if you have:
  • Eczema
  • Sunburned, windburned, or otherwise irritated skin
  • Sensitivity to the sun or if you go out in the sun often
  • Colitis
  • Crohn's disease
  • A history of colon inflammation from taking antibiotics (antibiotic-associated colitis)
  • Any allergies, including to foods, dyes, or preservatives.
Also, let your healthcare provider know if you are:
  • Pregnant or thinking of becoming pregnant
  • Breastfeeding.
You should also tell your healthcare provider about all other medications you are taking, including prescription and nonprescription medicines, vitamins, and herbal supplements.

Specific Precautions and Warnings With Duac

Some warnings and precautions to be aware of before using this acne medicine include the following:
  • Duac is a topical medicine, which means it should only be applied to the skin. Do not get the medicine into your eyes, mouth, nose, or other body openings, as it can irritate these areas. If this does occur, wipe the area clean or gently rinse with water to remove the medicine.
  • This medication will increase your sensitivity to the sun. Therefore, you should minimize your sun exposure and avoid artificial sun (such as sunlamps and tanning beds) while you are using it. Wear a PABA-free sunscreen and protective clothing, such as a hat, when you are out in the sun. Your healthcare can recommend an appropriate sunscreen.
  • Like all antibiotics, Duac may increase the risk for developing a secondary skin infection, such as a fungal or yeast infection. Stop using this medicine and contact your healthcare provider if you develop a yeast infection or notice signs of a skin or nail infection, such as a red, scaly, itchy rash or discolored, painful, or swollen nails.
  • You should not use other topical acne medicines while using Duac, unless your healthcare provider tells you otherwise. Doing so may cause severe skin irritation. Also, avoid using abrasive cloths or cleansers, as they may irritate your skin.
  • Using more of this medicine than prescribed will not make your acne go away faster. Instead, it may cause more skin irritation, redness, and dryness.
  • Duac gel may bleach hair or colored fabric. Let the medicine dry completely before touching your skin to colored materials, such as clothing, bed sheets, or pillowcases.
  • This medicine can cause temporary or minor skin irritation, such as redness, burning, stinging, or dryness. Stop using this medicine and contact your healthcare provider if you develop severe or persistent skin irritation or skin swelling.
  • All antibiotics, including clindamycin (one of the active ingredients of Duac), may cause a potentially serious problem known as pseudomembranous colitis. This problem occurs when the antibiotic alters the normal bacteria in the body, allowing undesirable bacteria to overgrow.
Pseudomembranous colitis is unlikely to occur with topical antibiotic use; however, it is important to tell your healthcare provider about any bloody or watery diarrhea, as these may be signs of a serious problem.
  • Duac is a pregnancy Category C medication, which means it may not be safe to use during pregnancy. Talk with your healthcare provider about the risks and benefits of using this medicine when pregnant (see Duac and Pregnancy).
  • It is not known if Duac passes through breast milk. Therefore, if you are breastfeeding or plan to start, talk to your healthcare provider about using this product (see Duac and Breastfeeding).

Duac Acne Medication Information

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