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More Info on Duac Indications and How It Works

How Does Duac Work?

As mentioned, Duac combines two medications: benzoyl peroxide and clindamycin.
Clindamycin belongs to a class of antibiotics known as lincosamides. It works by binding to bacterial ribosomes (the parts of cells that make proteins) and interfering with their ability to make proteins, which are necessary for bacteria to grow and multiply. This helps stop the spread of the bacteria that contribute to acne (Propionibacterium acnes or P. acnes for short).
Benzoyl peroxide is also thought to work by killing P. acnes. It does this by releasing oxygen into the pores of the skin. Because P. acnes is a type of anaerobe, which means it lives without oxygen, the oxygen kills the bacteria. Benzoyl peroxide also helps soften and peel away the outer layer of the skin, which can open up clogged pores and help improve the skin's appearance.

Can Children Use Duac?

This medication is approved for use in adolescents who are at least 12 years old. It has not been adequately studied in younger age groups. Talk with your child's healthcare provider about the benefits and risks of using this acne medicine in children.

Is It Used for Off-Label Reasons?

On occasion, your healthcare provider may recommend this medicine for treating something other than acne. This would be known as an "off-label" use. Using Duac in someone younger than 12 years of age would be an example of an off-label use.

Duac Acne Medication Information

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