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Understanding Duac's Effects and Treatment Tips

Clinical Effects

In clinical studies, Duac reduced the number of inflammatory acne lesions (pimples) in people with moderate-to-moderately severe acne. In these studies, people using Duac had a more noticeable overall improvement in their acne than people using the individual medicines in Duac (clindamycin or benzoyl peroxide) or a placebo (a gel that does not contain any active ingredients).
In one study, people using Duac had 65 percent fewer acne lesions, on average, after 11 weeks of treatment. By comparison, clindamycin users had a 34 percent decrease, benzoyl peroxide users had a 36 percent decrease, and those who used a placebo had a 19 percent decrease.
It should be noted that in two clinical studies, Duac use was no more effective at reducing acne lesions than when clindamycin or benzoyl peroxide was used alone. In these studies, all three treatments reduced acne lesions by 38 to 57 percent. Duac has not been shown to reduce noninflammatory acne lesions, such as blackheads and whiteheads, more than just using benzoyl peroxide.

When and How to Use It

Some general considerations to keep in mind during treatment with Duac include the following:
  • This medication comes in the form of a gel. It is normally applied in a thin layer to the affected area(s) of the skin once daily in the evening.
  • Gently wash the affected area(s) with a mild cleanser, rinse with warm water, and pat dry before applying Duac.
  • This gel should only be applied to the skin. Avoid getting it in your eyes, nose, or mouth, as it can irritate these areas. Wash your hands thoroughly after applying it.
  • For the best results, apply the gel to the entire affected area(s), not just individual pimples.
  • To minimize the risk of excessive skin irritation, do not use astringents, alcohol-containing toners, or other medicated skin products while using Duac without your healthcare provider's approval.
  • Your skin will be more sensitive to the sun when you use this medicine. Avoid going out in the sun for long periods of time. Use sunscreen and wear protective clothing, such as a hat, while you are outside to protect your skin from the sun.
  • For the medication to work properly, it must be used as prescribed. Applying more gel, or using it more often, will not make it work faster or more effectively. Instead, it may irritate your skin.

Duac Acne Medication Information

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