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Duac and Pregnancy

As a pregnancy Category C medicine, Duac (clindamycin/benzoyl peroxide) may not be safe for women who are expecting. Because only one of the active ingredients in this drug has been studied in animals, all of the potential pregnancy risks cannot yet be ruled out. Therefore, pregnant women should only use this drug when the benefits outweigh the risks.

Can Pregnant Women Use Duac?

Duac® (clindamycin/benzoyl peroxide) is a topical prescription medication approved to treat acne in people 12 years of age and older. It is a combination of clindamycin and benzoyl peroxide. At this time, the full risks of using this medicine during pregnancy are still unknown. The manufacturer of Duac recommends that this drug only be given to a pregnant woman if clearly needed.

What Is Pregnancy Category C?

Duac is classified as a pregnancy Category C drug. The U.S. Food and Drug Administration (FDA) uses a category system to classify the possible risks to a fetus when a specific medicine is taken during pregnancy. Pregnancy Category C is given to medicines that have not been adequately studied in pregnant humans but have caused fetal harm in animal studies.
In addition, medicines that have not been studied in any pregnant women or animals are automatically given a pregnancy Category C rating.
Duac itself has not been studied in pregnant women or animals, and neither has benzoyl peroxide, one of the active ingredients in the medicine. Clindamycin, the other active ingredient in the medicine, did not appear to cause birth defects or other problems in the offspring when given to pregnant rats and mice.
When used by itself, clindamycin is considered a pregnancy Category B medicine. Pregnancy Category B is given to medicines that have not been adequately studied in pregnant humans but do not appear to cause fetal harm in animal studies. In fact, clindamycin is often used to treat certain bacterial infections during pregnancy.
Even though only a small amount of Duac is expected to be absorbed through the skin with normal use, all potential risks to an unborn child cannot yet be ruled out.
Using Duac to treat acne during pregnancy may not outweigh the possible risks. If you desire acne treatment while pregnant, talk to your healthcare provider about safe and effective acne treatment strategies.
Pregnancy and Pain

Duac Acne Medication Information

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