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Differin Warnings and Precautions

Before using Differin, tell your healthcare provider if you have eczema, any allergies, or a sunburn. Other warnings and precautions include avoiding contact between Differin and the skin around your eyes and mouth, and avoiding exposure to sunlight (including artificial sunlight from tanning booths). You may not be able to use this medicine if you have certain allergies, are pregnant, or are breastfeeding.

What Should I Tell My Healthcare Provider?

You should talk with your healthcare provider prior to using Differin® (adapalene) if you have:
  • Eczema
  • A sunburn
  • Any allergies, including allergies to medications, foods, dyes, or preservatives.
Also, let your healthcare provider know if you are:
  • Pregnant or thinking of becoming pregnant
  • Breastfeeding.
You should also tell your healthcare provider about any other medications you are taking, including prescription and nonprescription medicines, vitamins, and herbal supplements.

Specific Precautions and Warnings With Differin

Some warnings and precautions to be aware of with Differin include:
  • Avoid contact with the delicate skin around the eyes and mouth.
  • Avoid exposure to sunlight (including artificial sunlight, such as sun lamps or tanning booths), as this medication increases your sensitivity to the sun. Make sure to talk with your healthcare provider about a sunscreen that is appropriate for your skin type (and that will not make your acne worse).
  • Although some skin irritation, redness, and burning are to be expected when you first start Differin, make sure to let your healthcare provider know if extreme irritation occurs.
  • Generally, people with eczema should avoid this product, as this type of medication can cause severe skin irritation in people with eczema.
  • If you get a sunburn, stop using Differin until your skin has recovered.
  • Any area of skin treated with Differin should not be waxed, as this may cause skin damage.
  • Differin is unlikely to interact with medications, although some skin products could worsen irritation with Differin (see Differin Drug Interactions).
  • Differin is a pregnancy Category C medication, which means that it may not be safe for use during pregnancy, although the full risks are currently unknown (see Differin and Pregnancy for more information).
  • It is unknown if Differin passes through breast milk. Therefore, if you are breastfeeding a child, check with your healthcare provider (or your child's healthcare provider) before using Differin (see Differin and Breastfeeding).

Differin Medication Information

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