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BenzaClin Drug Interactions
You may not be able to use BenzaClin with certain other topical medications, including erythromycin skin products and other topical acne medicines. Using these products with BenzaClin may cause negative interactions, including skin reactions or decreased effectiveness of the drugs. Before starting acne treatment, make sure your healthcare provider knows about all other skin products you are using.
BenzaClin® (clindamycin/benzoyl peroxide) is a prescription medication used to treat acne. This product may react with a few other topical medications.
Some of the drugs that may lead to interactions with BenzaClin include but are not limited to:
- Erythromycin skin products, such as Akne-mycin®, Benzamycin®, Benzamycin® Pak, and Erythra-Derm™
- Other topical acne medications.
The following sections explain in detail the potentially negative reactions that can occur when BenzaClin is combined with any of the drugs listed above.
Erythromycin Skin Products
Clindamycin, one of the active ingredients in BenzaClin, can make erythromycin less effective. In general, these medications should not be used together.
Other Topical Acne Medications
Using BenzaClin with other acne medications may cause severe skin irritation, such as redness, dryness, burning, and stinging. Talk to your healthcare provider before using other acne lotions, creams, or gels while using BenzaClin.
It is possible that not all BenzaClin drug interactions were discussed in this article. Therefore, you should talk with your pharmacist or healthcare provider about the specific interactions that may apply to you.
Written by/reviewed by: Susan Lakey, PharmD, MPH
Last reviewed by: Kristi Monson, PharmD