When treating acne with
Accutane® (
isotretinoin), your healthcare provider will consider several factors, such as how you respond to the medication, your weight, and the severity of your acne.
For example, your healthcare provider may prescribe 20 mg
Accutane capsules to treat your acne. In most cases, the recommended dose of Accutane is 0.5 mg to 1 mg per kg of body weight (about 0.23 mg to 0.45 mg per pound) each day, divided into two daily doses. For adults with severe acne or acne limited mostly to the trunk of the body, a dose of 2 mg per kg (about 0.91 mg per pound) each day, divided into two daily doses, may be necessary.
Accutane capsules must be taken with food, as taking them on an empty stomach significantly decreases its absorption. You can only get a 30-day supply of Accutane at a time. Each time you need more, you will need a new prescription and a new authorization from the iPLEDGE program (the program designed to prevent birth defects caused by Accutane). If you are a woman of childbearing potential, you will need to have a negative
pregnancy test every month (done by a laboratory) and must use two different forms of birth control.
(Click Accutane Dosage for more information on using this medicine. This article also discusses tips on effectively using Accutane and covers the factors your healthcare provider will consider before recommending a dosage.)